High Potency Whole Food Vitamin D with Ubiquinol
Each capsule contains:
2,000 IU's of Whole Food Vitamin D, equaling 500% of the RDA
15 Milligrams of Ubiquinol, which is equivalent to 120 Milligrams of CoQ10.
Vitamin D is being called "the nutrient of the decade" by many scientists and researchers. The once fairly-innocuous vitamin is now celebrated as possibly the most important vitamin. Literally hundreds of studies over the past few years has established its much vaunted status, linking it to numerous mechanisms of health and vitality.
It is now commonly agreed that Vitamin D transcends the definition of a mere vitamin - it is actually a prohormone, and is essential to the health of most organs, including the brain, heart, skin, gonads, prostate gland, and mammary glands. Vitamin D receptors are also involved in immune regulation and mediate response to infection and inflammatory processes.
The bad news is that this vitamin, which has historically been thought to be sufficiently gained by sunlight exposure for 20 minutes a day, is now becoming deficient in spite of the sunlight. Average blood serum levels of Vitamin D have dropped over the past decade to the point that, according to a recent study, 77% of Americans have insufficient amounts (even in sunny places like Arizona). Obesity is one of the reasons for this increase because fat retains Vitamin D, making it less available to the rest of the body.
One major research study compared national deficiency studies (NHAMES) and found that there was a marked decline across the board. They suggested that the majority of children and adults in the United States (and almost all African and Mexican-Americans) are vitamin D insufficient.
Other mounting evidence shows that Vitamin D can support muscle strength and thereby reduce the incidence of falls, particularly in elderly and at-risk patients.
Vitamin D related to various conditions
Cardiovascular Disease - Vitamin D deficiency is associated with increased risk for cardiovascular events and mortality in a multi-ethnic study of atherosclerosis. Obesity is a major risk factor for cardiovascular disease. Studies confirm an association between obesity and Vitamin D deficiency, and low Vitamin D status is predictive of insulin resistance. Overweight women replete with Vitamin D shed pounds more successfully.
Bone & Muscle Pain - Vitamin D deficiency can lead to osteomalacia, resulting in weak muscles and bones. Symptoms of bone pain and muscle weakness can indicate inadequate Vitamin D levels.
Cancer - Scientists have been able to establish the biological impact of Vitamin D in cancer prevention, recognizing the vitamin's effects on cell proliferation. Vitamin D has a putative involvement in both primary and secondary prevention of prostate cancer and breast cancer as well as non-Hodgkin's lymphoma, melanoma, and other malignancies. One Finnish study found that subjects with the lowest levels of Vitamin D had three-fold higher risk of developing pancreatic cancer.
Mortality (Life Expectancy) - Possibly the most motivating reasons to take higher dosages of Vitamin D comes from a study of 3,400 French men, age 50 years and older, correlating vitamin D status with all-cause of mortality. Men with the lowest Vitamin D levels had a 44% higher death rate.
Pregnancy - The Canadian Pediatric Society recently recommended that pregnant women increase their intake of Vitamin D to 2,000 IU/day because of the beneficial effects to both the mother and child.
Athletics - Athletic trainers, cognizant of research suggesting that Vitamin D may augment muscle strength, are increasingly embracing oral supplementation and UV-light for purpose of performance enhancement.
Safety & recommended amounts of Vitamin D
The longtime government recommendation for Vitamin D intake in adults and older children was set at 400IU/day. This amount was determined based on the historical precedent that a teaspoon of cod liver oil delivered that much Vitamin D. (Really detailed science!!)
Some controversy exists between what constitutes "sufficiency," which is the amount needed to sustain normal levels of Vitamin D, and "deficiency," which is the amount needed to get levels up to normal, if depleted.
Sufficiency - According to leading researchers it is recommended to take between 1,000 and 4,000 IU/day. This is based on the latest research and the realization that additional amounts of Vitamin D are necessary due to our high-stress lifestyles and eating habits.
Deficiency - Recent studies determined that MS patients who were very deficient in Vitamin D had dramatically beneficial results when supplementing with between 5,000 and 8,000IU/day. Additional studies of patients with other debilitating diseases saw similar results. Moreover, in deficiency cases like MS, supplementing at only 1,000IU per day actually caused relapses in some cases.
Can I overdose on Vitamin D because it is fat soluble?
The key to understanding overdose risk lies with understanding the difference between whole food versus synthetic vitamins.
Even mainstream researchers for major publishers, such as the Washington Post, understand the difference between whole food and synthetic vitamins. They stated: "You can't get too much Vitamin D from sun or food." That is very true. If you are taking a synthetic supplement Vitamin D, you must realize the liver has to do the processing and this can put a strain on the liver.
That is why all fat soluble vitamin supplements, like Vitamin A, have limits placed on them for pregnant women and the elderly - because synthetic versions can and do cause problems when used in excess. Always stick with whole food vitamins when possible.
What form of Vitamin D should I take?
Supplemental Vitamin D has been found to be beneficial. A recent study showed that Vitamin D supplementation was associated with an increased life span of 7%. The subjects were healthy, middle aged or elderly people. They took around 1,000 to 2,000 IU/day.
Vitamin D supplements were only available in two forms until now. Vitamin D2 (ergocalciferol) and Vitamin D3 (cholecalciferal). Vitamin D2 is manufactured by the UV irradiation of ergosterol in yeast. Vitamin D3 is manufactured by the irradiation of lanolin (sheep wool). Research has leaned toward the vitamin D3 form because it is typically absorbed better - as much as 300% better.
Health food stores generally carry Vitamin D3. The best form of Vitamin D supplementation would be to get it in its whole food form as it exists in nature.
Now available is a Vitamin D supplement that has been cultured in a live yeast, probiotics, enzyme and whole food matrix. This creates all the components for the end result of a "high potency" whole food Vitamin D supplement. What do your senses tell you? Taking a synthetic Vitamin D supplement or a cultured whole food based one? Of course the whole food supplement makes more sense.
Which nutrient would compliment Vitamin D best in a single formula?
Vitamin D has a tremendous impact on many of the body's physiological processes from allergic diseases, depression, schizophrenia, cognitive impairment, pre-eclampsia, fibromyalgia, Parkinson's disease, polycystic ovary syndrome, and benign prostatic hyperplasia. This impact shows the ubiquitous nature of Vitamin D. Because Vitamin D is present throughout the cellular tissues of the body and it is fat soluble, it makes it a perfect companion with CoQ10 because CoQ10 is ubiquitous (present in every cell and tissue) and it is fat soluble...
CoQ10 was discovered in 1957, but it was known by a different name. It was called Ubiquinone. The reason it was called Ubiquinone was because the nutrient was found to be "ubiquitous," which means it was present in every cell and tissue of the body. This is important to know because it helps us realize how important this nutrient is.
Every single cell in the body uses this "spark plug" nutrient to ignite the cellular energy needed for each and every cell to do its job. Although CoQ10 is present in every cell and tissue, it is concentrated most in the heart because the heart requires a constant energy flow to keep it beating and keep us alive. It is very important to understand that the body doesn't use CoQ10 in the Ubiquinone form, although that is the main form of CoQ10 sold to consumers. The body actually breaks down or "reduces" the Ubiquinone down to Ubiquinol. It is Ubiquinol that is then utilized by the cells of the body. If the body is already under stress, it is hard to do this.
The body uses a complex process to reduce Ubiquinone to Ubiquinol. This process demands Vitamin B6, B12, Folic Acid, Niacinimide, Panothenic Acid and Vitamin C from the body. It also uses various amino acids if they are available. If they are not available in the blood stream, they will be taken from the muscles. The body then utilizes and stores the Ubiquinol form of CoQ10.
Scientists have known for some time that higher CoQ10 levels (Ubiquinol) are typically linked to better health; however, Optimal Health Systems has had reservations about introducing a CoQ10 supplement (Ubiquinone) because of the other nutrients and energy the body will require to convert it to useable CoQ10 (Ubiquinol).
Today, that problem has finally been solved.
CoQ10 is a fat soluble substance and therefore it is absorbed with fats in our diet like Vitamin D. Other places that CoQ10 is concentrated in the body are other areas that have a high metabolic activity rate. This includes not only the heart, but also other muscles, the liver, kidneys and brain. CoQ10's primary function is to produce cellular energy to keep the body efficient, healthy and immune from disease. Because of this, CoQ10 is also a very powerful antioxidant.
CoQ10 has been called a "conditionally essential" nutrient until now because the body can synthesize it from certain nutrients. Because of our abuse of processed foods that deplete our enzyme levels, and other factors commiserate with the Western diet and lifestyle, CoQ10 levels have been shown to be depleted as we age - starting from the early 20's. That depletion is one of the many variables that have made us vulnerable to today's common disease conditions.
Documented health benefits associated with CoQ10:
There is a large body of evidence on the beneficial effects of CoQ10 supplementation.
Cardiovascular Disease - CoQ10 protects LDL fats from oxidizing which helps prevent heart disease. CoQ10 levels have also been shown to be low in the majority of heart failures. The bottom line with heart disease conditions is that higher amounts of CoQ10 in the system helps keep the heart strong and healthy.
Neurodegenerative Disease - These diseases include Huntington's, Parkinson's, Alzheimer's and Lou Gehrig's Disease. High dosage supplementation of CoQ10 in these conditions has been very promising as of late.
Neuromuscular diseases such as muscular dystrophy, diabetes, cancer, asthma, migraines, immune disorders, HIV/AIDS, periodontal disease, chronic fatigue syndrome and male infertility have all been linked to low levels of CoQ10. Studies on CoQ10 supplementation overall are very promising, but the research is especially favorable with these diseases.
The need to supplement CoQ10
It is important to supplement this nutrient because the production of CoQ10 declines with age. The nutrient is found in organ meats, but the typical western diet only supplies about 5mg of CoQ10 daily. Moreover, as mentioned earlier, the body then has to reduce that form into the useable Ubiquinol form for the cells to utilize and derive energy from.
Why has OHS waited this long to bring a CoQ10 product to the market?
Until a few years ago, the only form of CoQ10 supplement on the market was the Ubiquinone form. Also, the most prominent studies showing the marked decline of CoQ10 in adults after the age of 20 have only recently been completed. The reduced form of CoQ10 is finally available on the market, which caused our product development team to get excited. The timing was right to include it as a complimentary part of our new Vitamin D formula!
The research is very clear that CoQ10 in the Ubiquinol reduced form is absorbed better and that it is up to eight times more effective than the Ubiquinone form. OHS has taken this knowledge and improved it even further by taking the powerful CoQ10 Ubiquinol and putting it in an organic-based cultured media that contains whole foods, probiotics, plant enzymes, organic yeast and pea. This "cultured media" binds with the Ubiquinol to create an even more efficient delivery catalyst.
Research has demonstrated that CoQ10 products are absorbed better when taken with food. By putting the reduced form of CoQ10 in a live food culture, the results are amazing.
What amounts are recommended?
Because CoQ10 is absorbed and utilized eight times better than the widely sold Ubiquinone form, you will only need 15mg to get the benefits of 120mg of the Ubiquinone form. It is recommended to take 60mg CoQ10 (Ubiquinol form) a day as a loading phase for two weeks in normal, healthy adults and then 30mg a day as a maintenance phase. This would be 4 capsules a day for two weeks and then 2 capsules a day thereafter.
Are higher amounts used and proven to be safe in clinical conditions?
The short answer is yes.
The safety of high doses over long periods is very well documented in the literature. The only side effects reported with small number of subjects are mild gastrointestinal symptoms such as nausea and stomach upset when very high dosages were used. In a recent study, doses as high as 3000mg a day (Ubiquinone) which would be equivalent to 375mg of OHS's Ubiquinol, were found to be safe and tolerable in patients with Parkinson's Disease. In a recent trial on the safety of CoQ10 in its reduced form as ubiquinol in human subjects showed dosages of 300mg daily for months was found to be safe and effective. Higher dosages over 300mg of Ubiquinol daily were not tested in that study. Although these dosages are safe, the research shows that they are not needed. 60mg of Ubiquinol (4 capsules) is equivalent to 480mg of Ubiquinone and that is considered a high potency dosage.
Why combine Whole Food Vitamin D and CoQ10 together?
As shown earlier, both Vitamin D and CoQ10 are becoming depleted in the majority of the population - typically as we age past 20. Both of these nutrients are found in almost every tissue and cell in the body (ubiquitous). Both nutrients play a profound role in cardiovascular health, muscle strength and viability (including the heart). And both are extremely beneficial for overall longevity and high quality of life.
Instead of taking a synthetic form of Vitamin D or CoQ10 in the Ubiquinone form (like most people do), you now have the ability to supplement with whole food nutrients assembled in the most absorbable and useable way - just as nature intended!
Longevi-D is being widely accepted as the first and only high potency whole food Vitamin D product. And, with the most absorbable and usable form of CoQ10 (Ubiquinol) included, it is expected to be another industry-leading product introduced by Optimal Health Systems.
NOTE: Because OHS's Longevi-D contains 15mg CoQ10 (Ubiquinol) and 2000 IU of Vitamin D per capsule, it is recommended to take 4 capsules a day for two weeks as a loading phase and then reduce to 2 capsules daily for therapeutic maintenance.
*These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease.